The Stanford Neuro-Oncology Program Adult Clinical Trials

Recurrent High Grade Glioma

Phase II/III Randomized Study of Toca 511 & Toca FC Versus SOC in Subjects Undergoing Surgery for Recurrent GBM/AA
PI: Seema Nagpal
Clinicaltrials.gov#: NCT02414165

Phase Ib/II, Multicenter, Open-label Study of ACP-196 in Subjects with Recurrent Glioblastoma Multiforme (GBM)
PI: Lawrence Recht
Clinicaltrials.gov#: NCT02586857

A Phase I BPM31510 + Vitamin K in High Grade Glioma that has Recurred on Bevacizumab Containing Regimen
PI: Seema Nagpal
Clinicaltrials.gov#: NCT03020602

Brain Metastases

Phase II Etirinotecan Pegol in Refractory Brain Metastases & Advanced Lung CA / Metastatic Breast CA
PI: Joel Neal
Clinicaltrials.gov#: NCT02312622

A Phase II Study to Evaluate the Efficacy and Safety of Oral Ceritinib in Patients with ALK-Positive NSCLC Metastatic to the Brain and/or to Leptomeninges
PI: Joel Neal
Clinicaltrials.gov#: NCT02336451

Memantine Hydrochloride and Whole-Brain Radiotherapy With or Without Hippocampal Avoidance in Reducing Neurocognitive Decline in Patients with Brain Metastases
PI: Scott Soltys
Clinicaltrials.gov#: NCT02360215