Pancreatoblastoma
Supplemental Studies
Immunohistology
- Acinar component
- Trypsin, chymotrypsin positive
- Lipase variable
- Alpha fetoprotein variable
- Squamoid nests
- CK 8, 18, 19 positive
- CK5/6 occasionally focal
- Endocrine differentiation
- Chromogranin, synaptophysin positive scattered cells in 2/3 of cases
- Islet polypeptides usually negative
