Menetrier Disease
Differential Diagnosis
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Superficial biopsies showing foveolar hyperplasia may appear identical to:
- Reflux gastropathy
- Localized hyperplasia adjacent to other lesions
- Hyperplastic polyps
- Cronkhite-Canada polyps
- Full thickness specimens and clinical and endoscopic correlation are required to demonstrate the extent of foveolar hyperplasia and atrophy of oxyntic glands or the presence of a discrete polyp
| Cronkhite-Canada Syndrome, Gastric Involvement | Menetrier Disease |
| Hair, nail, skin pigmentation changes present | No associated extra-GI lesions |
| Colorectal polyps very common | Not associated with colorectal polyps |
