Pubertal Macromastia
Differential Diagnosis
Pubertal Macromastia | Juvenile Fibroadenoma |
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Diffuse, not circumscribed | Circumscribed |
Fibrous or fatty stroma | Cellular stroma |
Rare | More common as a cause of adolescent breast enlargement |
Pubertal Macromastia | Phyllodes Tumor |
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Young age (10-17 years) | Almost all over 30 years |
No discrete mass | Mass usually present |
No broad papillae | Broad papillae inserted into spaces |
Paucicellular stroma | Cellular stroma |
No stromal mitotic figures | May have stromal mitotic activity |
No stromal atypia | Stromal atypia may be present |
Pubertal Macromastia | Juvenile Papillomatosis |
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Diffuse | Circumscribed |
Massive enlargement | Mean size 4 cm |
Usually bilateral | Usually solitary |
Predominantly stromal process | Prominent cysts |