Plasmacytoid Urothelial (Transitional Cell) Carcinoma
Definition
- Aggressive subtype of urothelial carcinoma with plasmacytoid features
Note
- Usual papillary urothelial carcinoma is covered separately
Diagnostic Criteria
- Simulates a hematolymphoid neoplasm
- Discohesive invasive pattern
- Eccentric nuclei
- Prominent eosinophilic cytoplasm
- Intracytoplasmic mucin positive lumens may be present
- Frequently presents at high stage
- Frequently exhibits peritoneal surface spread
Robert V Rouse MD
Department of Pathology
Stanford University School of Medicine
Stanford CA 94305-5342
Original posting/updates: 10/20/12