Malignant vascular neoplasms are LMO2+ with the exception of epithelioid vascular malignancies of bone and pleura. A, B, and C, Kaposi sarcoma (A, ×200) and epithelioid hemangioendothelioma associated with a muscular arteriole (B, ×200) are LMO2+, whereas an epithelioid hemangioendothelioma of bone (C, ×200) is LMO2− (arrow, internal positive control tumor vasculature). D, E, and F, An angiosarcoma of the colon (D, ×200) and a pericardial epithelioid angiosarcoma (E, ×200) are LMO2+, whereas a pleural epithelioid angiosarcoma (F, ×200) is LMO2− (arrows, internal positive control tumor vasculature).